History of Interstates and U.S. Highways in Mississippi
Mississippi's network of Interstates and U.S. highways has been integral to its development, linking agricultural regions, manufacturing hubs, and the Gulf Coast with the rest of the country. Early roads like U.S. 49 and U.S. 61 played a key role in facilitating commerce and travel throughout the state. The establishment of the Interstate Highway System in the 1950s brought major Interstates like I-10, I-20, and I-55, which now serve as vital transportation corridors for both local and interstate traffic.
These highways are crucial for the state's economy, with major routes like I-55 and I-20 providing access to important agricultural, industrial, and commercial centers. Mississippi’s location as a crossroads between the Deep South and the Midwest also makes its highways critical for freight transport. Additionally, highways such as U.S. 90 along the Gulf Coast are popular tourist routes, offering access to beaches and cultural destinations.
Mississippi is actively working to enhance its highways, with ongoing projects focused on improving key corridors and expanding capacity to handle increased traffic. Recent upgrades include the widening of I-55 and improvements to I-20, while future projects aim to modernize infrastructure and bolster economic growth by ensuring that the state’s transportation network remains efficient and reliable.
Busiest and Longest Federal Interstates and U.S. Highways in Mississippi
| Interstate or Highway | Length (mi) | Length (km) | Southern or Western Terminus | Northern or Eastern Terminus | Created |
|---|---|---|---|---|---|
| I-55 | 290 | 467 | Louisiana Border | Tennessee Border | 1957 |
| I-20 | 154 | 248 | Louisiana Border | Alabama Border | 1957 |
| I-10 | 77 | 124 | Louisiana Border | Alabama Border | 1957 |
| U.S. 49 | 299 | 481 | Gulfport, MS | Mississippi Delta | 1926 |
| U.S. 61 | 298 | 480 | Louisiana Border | Tennessee Border | 1926 |
| U.S. 82 | 190 | 306 | Arkansas Border | Alabama Border | 1926 |
| U.S. 90 | 76 | 122 | Louisiana Border | Alabama Border | 1926 |
| U.S. 84 | 159 | 256 | Louisiana Border | Alabama Border | 1926 |
| U.S. 11 | 141 | 227 | Louisiana Border | Alabama Border | 1926 |
| U.S. 98 | 110 | 177 | Louisiana Border | Alabama Border | 1926 |
Mississippi Designated Highways
Mississippi Interstate Highway 10, I-10 E
Mississippi Interstate Highway 10, I-10 W
Mississippi Interstate Highway 20, I-20 E
Mississippi Interstate Highway 20, I-20 W
Mississippi Interstate Highway 55, I 55 Frontage Rd N
Mississippi Interstate Highway 55, I 55 West Frontage Rd
Mississippi Interstate Highway 55, I-55 N
Mississippi Interstate Highway 55, I-55 S
Mississippi Interstate Highway 55, W Cunningham Ave
Mississippi Interstate Highway 59, I-59 N
Mississippi Interstate Highway 59, I-59 S
Mississippi Interstate Highway 69, I-69 N
Mississippi Interstate Highway 69, I-69 S
Mississippi Interstate Highway 110, I-110 N
Mississippi Interstate Highway 110, I-110 S
Mississippi Interstate Highway 220, I-220 N
Mississippi Interstate Highway 220, I-220 S
Mississippi US Highway 11, 22nd Ave S
Mississippi US Highway 11, B St
Mississippi US Highway 11, Bouie St
Mississippi US Highway 11, Broadway Dr
Mississippi US Highway 11, Cross St
Mississippi US Highway 11, E Front St
Mississippi US Highway 11, E Pine St
Mississippi US Highway 11, Ellisville Blvd
Mississippi US Highway 11, Gordon St
Mississippi US Highway 11, Gunn Dr
Mississippi US Highway 11, Highway 11 and 80
Mississippi US Highway 11, Highway 11 Moselle
Mississippi US Highway 11, Highway 11 N Sandersville
Mississippi US Highway 11, Mobile St
Mississippi US Highway 11, N 2nd Ave
Mississippi US Highway 11, N Front St
Mississippi US Highway 11, N Heber Ladner Dr
Mississippi US Highway 11, Pine St
Mississippi US Highway 11, Russell Dr
Mississippi US Highway 11, Spec Wilson Blvd
Mississippi US Highway 11, Susie B Ruffin Ave
Mississippi US Highway 11, Teresa St
Mississippi US Highway 11, U S Highway 11
Mississippi US Highway 11, US-11
Mississippi US Highway 11, W Front St
Mississippi US Highway 11, W Pine St
Mississippi US Highway 45, N Jefferson St
Mississippi US Highway 45, Plymouth Bluff Access Rd
Mississippi US Highway 45, S Jefferson St
Mississippi US Highway 45, US-45
Mississippi US Highway 45, US-45 Alt
Mississippi US Highway 45, US-45 Alt N
Mississippi US Highway 45, US-45 Alt S
Mississippi US Highway 45, US-45 Bus
Mississippi US Highway 45, US-45 N
Mississippi US Highway 45, US-45 S
Mississippi US Highway 49, 25th Ave
Mississippi US Highway 49, Azalea Dr N
Mississippi US Highway 49, Azalea Dr S
Mississippi US Highway 49, Martin Luther King Dr
Mississippi US Highway 49, Medgar Evers Blvd
Mississippi US Highway 49, N Jerry Clower Blvd
Mississippi US Highway 49, Simpson Highway 49
Mississippi US Highway 49, U S Highway 49
Mississippi US Highway 49, US-49
Mississippi US Highway 49, US-49 N
Mississippi US Highway 49, US-49 S
Mississippi US Highway 49e, Main St
Mississippi US Highway 49e, US-49e
Mississippi US Highway 49W, Halay Barbour Pkwy
Mississippi US Highway 49W, Martin Luther King Jr Dr
Mississippi US Highway 49W, N Martin Luther King Jr Dr
Mississippi US Highway 49W, N Oak Ave
Mississippi US Highway 49W, S Martin Luther King Jr Dr
Mississippi US Highway 49W, S Oak Ave
Mississippi US Highway 49W, US-49W
Mississippi US Highway 51, Caldwell Dr
Mississippi US Highway 51, Commerce St
Mississippi US Highway 51, E Cunningham Ave
Mississippi US Highway 51, Front St
Mississippi US Highway 51, Highway 51 MM
Mississippi US Highway 51, Jackson Ave
Mississippi US Highway 51, Laurel St
Mississippi US Highway 51, Martin Luther King Blvd
Mississippi US Highway 51, Mississippi St
Mississippi US Highway 51, N Applegate St
Mississippi US Highway 51, N Broadway
Mississippi US Highway 51, N Clark Ave
Mississippi US Highway 51, N Dr Martin Luther King Jr Blvd
Mississippi US Highway 51, N Jackson St
Mississippi US Highway 51, N Liberty St
Mississippi US Highway 51, N Panola St
Mississippi US Highway 51, N State St
Mississippi US Highway 51, Northwest Ave
Mississippi Interstate Highway 10, I-10 W
Mississippi Interstate Highway 20, I-20 E
Mississippi Interstate Highway 20, I-20 W
Mississippi Interstate Highway 55, I 55 Frontage Rd N
Mississippi Interstate Highway 55, I 55 West Frontage Rd
Mississippi Interstate Highway 55, I-55 N
Mississippi Interstate Highway 55, I-55 S
Mississippi Interstate Highway 55, W Cunningham Ave
Mississippi Interstate Highway 59, I-59 N
Mississippi Interstate Highway 59, I-59 S
Mississippi Interstate Highway 69, I-69 N
Mississippi Interstate Highway 69, I-69 S
Mississippi Interstate Highway 110, I-110 N
Mississippi Interstate Highway 110, I-110 S
Mississippi Interstate Highway 220, I-220 N
Mississippi Interstate Highway 220, I-220 S
Mississippi US Highway 11, 22nd Ave S
Mississippi US Highway 11, B St
Mississippi US Highway 11, Bouie St
Mississippi US Highway 11, Broadway Dr
Mississippi US Highway 11, Cross St
Mississippi US Highway 11, E Front St
Mississippi US Highway 11, E Pine St
Mississippi US Highway 11, Ellisville Blvd
Mississippi US Highway 11, Gordon St
Mississippi US Highway 11, Gunn Dr
Mississippi US Highway 11, Highway 11 and 80
Mississippi US Highway 11, Highway 11 Moselle
Mississippi US Highway 11, Highway 11 N Sandersville
Mississippi US Highway 11, Mobile St
Mississippi US Highway 11, N 2nd Ave
Mississippi US Highway 11, N Front St
Mississippi US Highway 11, N Heber Ladner Dr
Mississippi US Highway 11, Pine St
Mississippi US Highway 11, Russell Dr
Mississippi US Highway 11, Spec Wilson Blvd
Mississippi US Highway 11, Susie B Ruffin Ave
Mississippi US Highway 11, Teresa St
Mississippi US Highway 11, U S Highway 11
Mississippi US Highway 11, US-11
Mississippi US Highway 11, W Front St
Mississippi US Highway 11, W Pine St
Mississippi US Highway 45, N Jefferson St
Mississippi US Highway 45, Plymouth Bluff Access Rd
Mississippi US Highway 45, S Jefferson St
Mississippi US Highway 45, US-45
Mississippi US Highway 45, US-45 Alt
Mississippi US Highway 45, US-45 Alt N
Mississippi US Highway 45, US-45 Alt S
Mississippi US Highway 45, US-45 Bus
Mississippi US Highway 45, US-45 N
Mississippi US Highway 45, US-45 S
Mississippi US Highway 49, 25th Ave
Mississippi US Highway 49, Azalea Dr N
Mississippi US Highway 49, Azalea Dr S
Mississippi US Highway 49, Martin Luther King Dr
Mississippi US Highway 49, Medgar Evers Blvd
Mississippi US Highway 49, N Jerry Clower Blvd
Mississippi US Highway 49, Simpson Highway 49
Mississippi US Highway 49, U S Highway 49
Mississippi US Highway 49, US-49
Mississippi US Highway 49, US-49 N
Mississippi US Highway 49, US-49 S
Mississippi US Highway 49e, Main St
Mississippi US Highway 49e, US-49e
Mississippi US Highway 49W, Halay Barbour Pkwy
Mississippi US Highway 49W, Martin Luther King Jr Dr
Mississippi US Highway 49W, N Martin Luther King Jr Dr
Mississippi US Highway 49W, N Oak Ave
Mississippi US Highway 49W, S Martin Luther King Jr Dr
Mississippi US Highway 49W, S Oak Ave
Mississippi US Highway 49W, US-49W
Mississippi US Highway 51, Caldwell Dr
Mississippi US Highway 51, Commerce St
Mississippi US Highway 51, E Cunningham Ave
Mississippi US Highway 51, Front St
Mississippi US Highway 51, Highway 51 MM
Mississippi US Highway 51, Jackson Ave
Mississippi US Highway 51, Laurel St
Mississippi US Highway 51, Martin Luther King Blvd
Mississippi US Highway 51, Mississippi St
Mississippi US Highway 51, N Applegate St
Mississippi US Highway 51, N Broadway
Mississippi US Highway 51, N Clark Ave
Mississippi US Highway 51, N Dr Martin Luther King Jr Blvd
Mississippi US Highway 51, N Jackson St
Mississippi US Highway 51, N Liberty St
Mississippi US Highway 51, N Panola St
Mississippi US Highway 51, N State St
Mississippi US Highway 51, Northwest Ave
Mississippi US Highway 51, S Applegate St
Mississippi US Highway 51, S Broadway
Mississippi US Highway 51, S Broadway St
Mississippi US Highway 51, S Clark Ave
Mississippi US Highway 51, S Extension St
Mississippi US Highway 51, S Jackson St
Mississippi US Highway 51, S Laurel St
Mississippi US Highway 51, S Liberty St
Mississippi US Highway 51, S Martin Luther King Dr
Mississippi US Highway 51, S Panola St
Mississippi US Highway 51, S State St
Mississippi US Highway 51, Second St
Mississippi US Highway 51, US-51
Mississippi US Highway 51, US-51 N
Mississippi US Highway 51, US-51 S
Mississippi US Highway 51, W Cunningham Ave
Mississippi US Highway 51, W Georgia Ave
Mississippi US Highway 61, Church St
Mississippi US Highway 61, Devereaux Dr
Mississippi US Highway 61, E Franklin St
Mississippi US Highway 61, Holland St
Mississippi US Highway 61, Hollywood Rd
Mississippi US Highway 61, Main St
Mississippi US Highway 61, N Dr ML King Jr St
Mississippi US Highway 61, SGT Prentiss Dr
Mississippi US Highway 61, St Catherine St
Mississippi US Highway 61, US-61
Mississippi US Highway 61, US-61 N
Mississippi US Highway 61, US-61 S
Mississippi US Highway 72, US-72
Mississippi US Highway 78, US-78 E
Mississippi US Highway 78, US-78 W
Mississippi US Highway 80, 2nd St
Mississippi US Highway 80, Anderson Rd
Mississippi US Highway 80, Clay St
Mississippi US Highway 80, E Government St
Mississippi US Highway 80, E Third St
Mississippi US Highway 80, Jackson Ave
Mississippi US Highway 80, Magnolia St
Mississippi US Highway 80, Northside Dr
Mississippi US Highway 80, Old Highway 80
Mississippi US Highway 80, Second St
Mississippi US Highway 80, US-80
Mississippi US Highway 80, Vicksburg St
Mississippi US Highway 80, W Government St
Mississippi US Highway 80, W Madison St
Mississippi US Highway 80, W Third St
Mississippi US Highway 82, Dr Martin Luther King Jr Dr E
Mississippi US Highway 82, Dr Martin Luther King Jr Dr W
Mississippi US Highway 82, US-82
Mississippi US Highway 82, US-82 Byp
Mississippi US Highway 82, US-82 E
Mississippi US Highway 82, US-82 W
Mississippi US Highway 84, Chantilly St
Mississippi US Highway 84, Devereaux Dr
Mississippi US Highway 84, Franklin St
Mississippi US Highway 84, Jefferson St
Mississippi US Highway 84, N 16th Ave
Mississippi US Highway 84, N Canal St
Mississippi US Highway 84, S 16th Ave
Mississippi US Highway 84, S Canal St
Mississippi US Highway 84, US-84
Mississippi US Highway 84, W 5th St
Mississippi US Highway 90, Beach Blvd
Mississippi US Highway 90, Beach Dr
Mississippi US Highway 90, Bienville Blvd
Mississippi US Highway 90, Denny Ave
Mississippi US Highway 90, E Beach Blvd
Mississippi US Highway 90, US-90
Mississippi US Highway 90, W Beach Blvd
Mississippi US Highway 98, E Presley Blvd
Mississippi US Highway 98, Hardy St
Mississippi US Highway 98, Lawrence St
Mississippi US Highway 98, US-98
Mississippi US Highway 98, US-98 E
Mississippi US Highway 98, US-98 W
Mississippi US Highway 98, W Presley Blvd
Mississippi US Highway 149, E Broadway St
Mississippi US Highway 149, US-149
Mississippi US Highway 149, W Broadway St
Mississippi US Highway 278, E Main St
Mississippi US Highway 278, N Davis Ave
Mississippi US Highway 278, N State St
Mississippi US Highway 278, S Davis Ave
Mississippi US Highway 278, S State St
Mississippi US Highway 278, US-278
Mississippi US Highway 278, US-278 E
Mississippi US Highway 278, US-278 W
Mississippi US Highway 278, W Main St
Mississippi US Highway 425, John R Junkin Dr
Mississippi US Highway 425, US-425
Mississippi US Highway 51, S Broadway
Mississippi US Highway 51, S Broadway St
Mississippi US Highway 51, S Clark Ave
Mississippi US Highway 51, S Extension St
Mississippi US Highway 51, S Jackson St
Mississippi US Highway 51, S Laurel St
Mississippi US Highway 51, S Liberty St
Mississippi US Highway 51, S Martin Luther King Dr
Mississippi US Highway 51, S Panola St
Mississippi US Highway 51, S State St
Mississippi US Highway 51, Second St
Mississippi US Highway 51, US-51
Mississippi US Highway 51, US-51 N
Mississippi US Highway 51, US-51 S
Mississippi US Highway 51, W Cunningham Ave
Mississippi US Highway 51, W Georgia Ave
Mississippi US Highway 61, Church St
Mississippi US Highway 61, Devereaux Dr
Mississippi US Highway 61, E Franklin St
Mississippi US Highway 61, Holland St
Mississippi US Highway 61, Hollywood Rd
Mississippi US Highway 61, Main St
Mississippi US Highway 61, N Dr ML King Jr St
Mississippi US Highway 61, SGT Prentiss Dr
Mississippi US Highway 61, St Catherine St
Mississippi US Highway 61, US-61
Mississippi US Highway 61, US-61 N
Mississippi US Highway 61, US-61 S
Mississippi US Highway 72, US-72
Mississippi US Highway 78, US-78 E
Mississippi US Highway 78, US-78 W
Mississippi US Highway 80, 2nd St
Mississippi US Highway 80, Anderson Rd
Mississippi US Highway 80, Clay St
Mississippi US Highway 80, E Government St
Mississippi US Highway 80, E Third St
Mississippi US Highway 80, Jackson Ave
Mississippi US Highway 80, Magnolia St
Mississippi US Highway 80, Northside Dr
Mississippi US Highway 80, Old Highway 80
Mississippi US Highway 80, Second St
Mississippi US Highway 80, US-80
Mississippi US Highway 80, Vicksburg St
Mississippi US Highway 80, W Government St
Mississippi US Highway 80, W Madison St
Mississippi US Highway 80, W Third St
Mississippi US Highway 82, Dr Martin Luther King Jr Dr E
Mississippi US Highway 82, Dr Martin Luther King Jr Dr W
Mississippi US Highway 82, US-82
Mississippi US Highway 82, US-82 Byp
Mississippi US Highway 82, US-82 E
Mississippi US Highway 82, US-82 W
Mississippi US Highway 84, Chantilly St
Mississippi US Highway 84, Devereaux Dr
Mississippi US Highway 84, Franklin St
Mississippi US Highway 84, Jefferson St
Mississippi US Highway 84, N 16th Ave
Mississippi US Highway 84, N Canal St
Mississippi US Highway 84, S 16th Ave
Mississippi US Highway 84, S Canal St
Mississippi US Highway 84, US-84
Mississippi US Highway 84, W 5th St
Mississippi US Highway 90, Beach Blvd
Mississippi US Highway 90, Beach Dr
Mississippi US Highway 90, Bienville Blvd
Mississippi US Highway 90, Denny Ave
Mississippi US Highway 90, E Beach Blvd
Mississippi US Highway 90, US-90
Mississippi US Highway 90, W Beach Blvd
Mississippi US Highway 98, E Presley Blvd
Mississippi US Highway 98, Hardy St
Mississippi US Highway 98, Lawrence St
Mississippi US Highway 98, US-98
Mississippi US Highway 98, US-98 E
Mississippi US Highway 98, US-98 W
Mississippi US Highway 98, W Presley Blvd
Mississippi US Highway 149, E Broadway St
Mississippi US Highway 149, US-149
Mississippi US Highway 149, W Broadway St
Mississippi US Highway 278, E Main St
Mississippi US Highway 278, N Davis Ave
Mississippi US Highway 278, N State St
Mississippi US Highway 278, S Davis Ave
Mississippi US Highway 278, S State St
Mississippi US Highway 278, US-278
Mississippi US Highway 278, US-278 E
Mississippi US Highway 278, US-278 W
Mississippi US Highway 278, W Main St
Mississippi US Highway 425, John R Junkin Dr
Mississippi US Highway 425, US-425