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The vast majority of operations at San Diego International Airport (SAN) are to the west. Landing at the airport from the east (the most common approach) offers dramatic closeup views of skyscrapers, Petco Park (home of the San Diego Padres), and the soaring, curving Coronado Bridge from the left side of the aircraft. On the right, Balboa Park, site of the 1915-1916 Panama-California Exposition, can be seen, along with the world famous San Diego Zoo and several freeways.

The approach from the east is steep, necessitated by terrain which drops from 266 feet to sea level in less than a mile. Aircraft normally descend at 317' per mile, but in San Diego they must descend at 376' per mile. San Diego's only runway is located at the base of a hill lined with several obstructions, including the I-5 freeway and trees in Balboa Park. Contrary to local lore, the parking structure off the end of the runway was built long after previous obstructions built up east of the I-5. The parking structure was then built up to this controlling limit. Aircraft clear the parking structure by the required 109 feet.
Aircraft arriving from the east do not land at the end of the runway as at most airports, but land at what is called a displaced threshold, located 1810 feet from the runway end, effectively shortening the landing distance to 7591 feet. Aircraft departing to the west use the east end of the runway as their departure point. A photo from the cockpit of an arriving aircraft clearly shows the approach and the displaced threshold.
Source: wikipedia